Description References
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4-(Aminomethyl)benzoic acid

Description References
Product Name
4-(Aminomethyl)benzoic acid
CAS No.
56-91-7
Chemical Name
4-(Aminomethyl)benzoic acid
Synonyms
Tranexamic EP Impurity D;PAMBA;H-(4)AMBZ-OH;Chrisma Pereira;Aminomethyl Acid;Aninomethylbenzoicacid;AMINOMETHYL BENZOIC ACID;AMinoMethyl benzoic acid on;Tranexamic Acid EP Impurity D;Benzoic acid, 4-(aMinoMethyl)-
CBNumber
CB7742381
Molecular Formula
C8H9NO2
Formula Weight
151.16
MOL File
56-91-7.mol
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4-(Aminomethyl)benzoic acid Property

Melting point:
≥300 °C (lit.)
Boiling point:
273.17°C (rough estimate)
Density 
1.2023 (rough estimate)
refractive index 
1.5810 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Base (Slightly), Water (Slightly, Heated, Sonicated)
pka
3.75±0.10(Predicted)
form 
Powder
color 
White to almost white
Water Solubility 
Slightly soluble in water. Insoluble in ethanol, benzene and chloroform.
BRN 
1100606
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
QCTBMLYLENLHLA-UHFFFAOYSA-N
CAS DataBase Reference
56-91-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39-26,37/39
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
5g
Price
$46.9
Updated
2024/03/01
Sigma-Aldrich
Product number
283746
Product name
4-(Aminomethyl)benzoic acid
Purity
97%
Packaging
25g
Price
$108
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
25g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
A0965
Product name
4-(Aminomethyl)benzoic Acid
Purity
>97.0%(HPLC)(T)
Packaging
100g
Price
$111
Updated
2024/03/01
Alfa Aesar
Product number
B23519
Product name
4-(Aminomethyl)benzoic acid, 97%
Packaging
25g
Price
$78.65
Updated
2024/03/01
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4-(Aminomethyl)benzoic acid Chemical Properties,Usage,Production

Description

4-(Aminomethyl)benzoic acid is a organic compound that can serve as a type 2 antifibrinolytic agent used in the treatment of fibrotic skin disorders, such as Peyronie's disease. It is believed that 4-(Aminomethyl)benzoic acid is effective to increase the oxygen uptake at the tissue level and enhance activity of monoamine oxidase, thus to promote the degradation of serotonin, which in excess, may lead to fibrotic changes. It is also administrated by mouth to treat several skin conditions including vitiligo, pemphigus, dermatomyositis, morphea, lymphoblastoma cutis and scleroderma. It is sometimes used in pill form by patients suffering from irritable bowel syndrome to treat the relevant gastrointestinal symptoms and applied in nutritional epidemiological studies to assess the completeness of 24-hour urine collection for the determination of urinary sodium, potassium, or nitrogen levels. Besides, it can also serve as nutritional supplements to darken gray hair, prevent hair loss, make skin look younger and prevent sunburn and its benefits are claimed for people with fatigue, irritability, depression, weeping eczema, scleroderma, patchy pigment loss in skin, and premature grey hair.

References

https://en.wikipedia.org/wiki/4-Aminobenzoic_acid
https://www.alfa.com/en/catalog/B23519/
https://pubchem.ncbi.nlm.nih.gov/compound/4-aminobenzoic_acid#section=Top
http://www.webmd.com/vitamins-supplements/ingredientmono-1004-PABA+PARA-AMINOBENZOIC+ACID+PABA.aspxactiveIngredientId=1004&activeIngredientName=PABA

Chemical Properties

white to light yellow crystal powde

Uses

4-(Aminomethyl)benzoic acid acts as an unnatural amino acid derivative. It is also used as a type 2 antifibrinolytic agent. Further, it reacts with 2-methyl-isothiourea sulfate to prepare 4-guanidinomethylbenzoic acid.

Uses

4-(Aminomethyl)benzoic acid (PAMBA) can be used in the synthesis of:

  • Cobalt carboxy phosphonates.
  • Apoptozole (Az), which has cellular potency to promote membrane trafficking of mutant cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel activity.
  • Cyclopeptide composed of L-glutamic acid and 3-aminobenzoic acid that can be used as receptors for a variety of cations and anions.
  • A bioactive peptide which has potent GPR54 (a G protein-coupled receptor) agonistic activity.

Uses

4-(Aminomethyl)benzoic Acid is a type 2 antifibrinolytic agent.

Definition

ChEBI: Aminomethylbenzoic acid is a member of benzoic acids.

4-(Aminomethyl)benzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(Aminomethyl)benzoic acid Suppliers

Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10194
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62
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
BOC Sciences
Tel
+16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19743
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Accela ChemBio Inc.
Tel
(+1)-858-699-3322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
19965
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58
Standardpharm Co. Ltd.
Tel
86-714-3992388
Email
overseasales1@yongstandards.com
Country
United States
ProdList
14336
Advantage
58
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10413
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63711
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-(817)863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19639
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58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
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65
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View Lastest Price from 4-(Aminomethyl)benzoic acid manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $15.00/kg
Min. Order
1kg
Purity
99.912%
Supply Ability
10ton
Release date
2024-04-26
Jinan Finer Chemical Co., Ltd
Product
4-(Aminomethyl)benzoic acid 56-91-7
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%
Supply Ability
500mt
Release date
2020-10-19
airuikechemical co., ltd.
Product
aminomethylbenzoic acid 56-91-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-10

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